Synthesis of Phenanthridine by Palladium Catalyzed Suzuki Coupling and Condensation Reaction

19 August 2021, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Transition metal catalyzed cross-coupling reactions such as Suzuki-Miyaura, Heck, Stille, Negishi, and Sonogashira reactions are likely to be the most power tool for the formation of C-C bonds for the past four decades. All these reactions have shown their widespread applicability ranging from academic area to research. Some of the reactions have also been applied in pharmaceuticals, agrochemicals, and fine material industries. Herein we report a one-pot strategy to achieve phenanthridine and analogous derivatives via Suzuki coupling of suitably substituted aromatic ortho-bromoaldehyde and ortho-aminobenzenboronic acid in quantitative to good yields

Keywords

organic synthesis
copling reaction
organometallic
materials chemistry

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