Low-Valent Tungsten Catalysis Enables Site-Selective Isomerization–Hydroboration of Unactivated Alkenes

12 July 2021, Version 1


A tungsten-catalyzed hydroboration of unactivated alkenes at distal C(sp3)–H bonds aided by native directing groups is described herein. The method is characterized by its simplicity, exquisite regio- and chemoselectivity and wide substrate scope, offering a complementary site-selectivity pattern to other metal-catalyzed borylation reactions and chain-walking protocols.


Supplementary materials

Supporting Info
Experimental Procedures, Analytical Data, and Copies of NMR Spectra
Crystallographic Information File - Compound 2b
Crystallographic Information File - Compound 2i
Crystallographic Information File - Compound 2n
Crystallographic Information File - Compound 3b


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