Catalysis

Low-Valent Tungsten Catalysis Enables Site-Selective Isomerization–Hydroboration of Unactivated Alkenes

Authors

Abstract

A tungsten-catalyzed hydroboration of unactivated alkenes at distal C(sp3)–H bonds aided by native directing groups is described herein. The method is characterized by its simplicity, exquisite regio- and chemoselectivity and wide substrate scope, offering a complementary site-selectivity pattern to other metal-catalyzed borylation reactions and chain-walking protocols.

Content

Thumbnail image of Manuscript.pdf

Supplementary material

Thumbnail image of Supporting Info.pdf
Supporting Info
Experimental Procedures, Analytical Data, and Copies of NMR Spectra
Thumbnail image of 2b.cif
2b.cif
Crystallographic Information File - Compound 2b
Thumbnail image of 2i.cif
2i.cif
Crystallographic Information File - Compound 2i
Thumbnail image of 2n.cif
2n.cif
Crystallographic Information File - Compound 2n
Thumbnail image of 3b.cif
3b.cif
Crystallographic Information File - Compound 3b