Ketones are among the most useful functional groups in organic synthesis. Here, we report the first carbonylative cross-electrophile coupling reaction that utilize carbon monoxide gas as the carbonyl source. The use of Pd/Rh cooperative catalysis enables the carbonylative coupling of easily accessible aryl triflates and aryl bromides. Unlike all previous carbonylative cross-electrophile coupling reactions, the method does not require addition of a stoichiometric metal reductant.
Experimental procedures and characterization data.