Ti(OiPr)4-Enabled Dual Photoredox and Nickel-Catalyzed Arylation and Alkenylation of  Cyclopropanols

Nastassia A. Varabyeva; Maryia V. Barysevich; Yauhen Aniskevich; Alaksiej Hurski

doi:10.26434/chemrxiv.14573148.v1

Organic Chemistry

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Ti(OiPr)4-Enabled Dual Photoredox and Nickel-Catalyzed Arylation and Alkenylation of Cyclopropanols

12 May 2021, Version 1

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Abstract

In this article, we report an application of cyclopropanols as coupling partners in the dual photoredox/nickel catalyzed reaction with aryl and vinyl bromides. We found that this cross-coupling proceeds smoothly in the presence of Ti(OiPr)₄ as an additive to provide β-aryl or γ,δ-unsaturated ketones.

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May 12, 2021 Version 1

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The content is available under CC BY NC ND 4.0

DOI

10.26434/chemrxiv.14573148.v1

Author’s competing interest statement

no conflict of interest