Abstract
Given
the complexity of separating nanoplastics from environmental samples, studies
have usually been conducted using synthetic polystyrene nanobeads. By
mechanical fragmentation in cryogenic conditions of daily-life plastic items, we
produced “true-to-life” nanoplastics (T2LNPs), that promises to give a true insight
into the interaction with biological systems. T2LNPs have been fully
characterized by Fourier transform Infrared spectroscopy and by Atomic Force
Microscopy. They result in populations of spheroidal nanoparticles with a broad
multimodal size distribution. The mandatory need for a representative sample to
evaluate the potential effects of nanoparticles on human health and the
environment is demonstrated by the different protein corona identified on
T2LNPs and synthetic polystyrene nanobeads upon incubation with human plasma.
Content

Supplementary material

TrueToLifeNanoplastics SI ChemRxiv