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A Thermogelling Organic-Inorganic Hybrid Hydrogel with Excellent Printability, Shape Fidelity and Cytocompatibility for 3D Bioprinting

26 April 2021, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

In this study, an advanced hybrid ink was developed, based on a thermogelling block copolymer, alginate and clay. The reversible thermogelling and shear thinning properties polymer acts at the same time as a fugitive material on the macromolecular level and facilitates the cell-laden extrusion based bioprinting.

Keywords

poly(2-oxazoline)
thermogelling
stimulus-responsive hydrogels
fugitive support
alginate capsules
clay

Supplementary materials

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Video S1 Sol-gel transition of the hydrogel
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Video S2 Printability testing of the hydrogel
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Video S3 3D Printing of the hydrogel
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Version History

Apr 26, 2021 Version 1

Version Notes

first version submitted for peer review

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License

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The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.14447676.v1
D O I: 10.26434/chemrxiv.14447676.v1 [opens in a new tab]

Funding

Deutsche Forschungsgemeinschaft
Chinese Scholarship Council
Higher Education Commission Pakistan
Deutscher Akademischer Austauchdienst

Author’s competing interest statement

RL is listed as inventor on a patent pertinent to some materials in the present work. The authors declare no other competing financial interest.

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