Working Paper
Authors
- Chandra Bhan Pandey ,
- Vikram Singh ,
- Susanta Ghanta ,
- Bhoopendra Twari ,
- BHOOPENDRA TIWARI
Centre of Biomedical Research
Abstract
Asymmetric syn-dihydroxylation
and dioxyacylation of alkenes have been well established. A direct method for
the enantioselective preparation of orthogonally protected syn-1,2-diols from alkenes is unprecedented. Here in, we report the
first enantioselective hypervalent iodine catalyzed syn-hydroxy-oxyacylation of enones. The orthogonally protected diols
were obtained with excellent diastereo- and regioselectivity under metal-free
condition. For these electron-deficient alkenes, even the syn-dihydroxylation and dioxyacylation have remained yet an
unfinished challenge.
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Supplementary material

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