Organic Chemistry

Formal Syntheses of Dictyodendrins B, C, and E by a Multi-substituted Indole Synthesis



The dictyodendrins are a family of marine alkaloids, which possess a highly substituted pyrrolo[2,3-c]carbazole core. This core structure can be regarded as a multi-substituted indole and aniline moiety. To achieve a concise synthesis of dictyodendrins, we planned to capitalize on our previously developed multi-substituted indole synthesis. By using this method along with two C–H functionalizations, formal syntheses of dictyodendrin B, C, and E were achieved.


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Supplementary material

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