Organic Chemistry

A Platform for Alkene Carbofunctionalization with Diverse Nucleophiles

Authors

Abstract

A general system achieving three-component intermolecular carbofunctionalization of alkenes is presented. A range of substituted alkenes are functionalized with α-bromo carbonyl electrophiles and nitrogen, oxygen, and carbon nucleophiles. Mechanistic findings support the intermediacy of a cyclic oxocarbenium ion.

Content

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Supplementary material

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ChemRxiv SI