Cambridge Open Engage home
What is Cambridge Open Engage?
How to Submit
Browse
About
News [opens in a new tab]

Versatile and Ligand-Free Copper-Catalyzed α-Arylations of Aromatic Ketones Using Diaryliodonium Salts

17 March 2021, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

A ligand and base free copper catalyzed synthetic methodology for the efficient alpha-arylation of aromatic ketones has been developed. The reaction of the ketone-derived silyl enol ethers with diaryliodonium salts led to the intermolecular C-C coupling displaying high functional group tolerance with a low catalyst loading.

Keywords

copper ion
Catalysis

Supplementary materials

Title
Description
Actions
Title
SI ChemxRiv
Description
Actions

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Version History

Mar 17, 2021 Version 1

Metrics

1,255
511
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
NC logo
NC
ND logo
ND
The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.14222372.v1
D O I: 10.26434/chemrxiv.14222372.v1 [opens in a new tab]

Author’s competing interest statement

No conflict of interest

Share