Organic Chemistry

Isoreticular Crystallization of Highly Porous Cubic Covalent Organic Cage Compounds

Abstract

Modular frameworks featuring well-defined pore structures in microscale domains establish tailor-made porous materials. For open molecular solids however, maintaining long-range order after desolvation is inherently challenging, since packing is usually governed by only a few supramolecular interactions. Here we report on two series of nanocubes obtained by co-condensation of two different hexahydroxy tribenzotriquinacenes (TBTQs) and benzene-1,4-diboronic acids (BDBAs) with varying linear alkyl chains in 2,5-position. nButyl groups at the apical position of the TBTQ vertices yielded soluble model compounds, which were analyzed by mass spectrometry and NMR spectroscopy. In contrast, methyl-substituted cages spontaneously crystallized as isostructural and highly porous solids with BET surface areas and pore volumes of up to 3426 m2 g−1 and 1.82 cm3 g−1. Single crystal X-ray diffraction and sorption measurements revealed an intricate cubic arrangement of alternating micro- and mesopores in the range of 0.97–2.2 nm that are fine-tuned by the alkyl substituents at the BDBA linker.

Content

Thumbnail image of 2021_02_Ivanova_manuscript_ChemRxiv.pdf

Supplementary material

Thumbnail image of 2021_02_Ivanova_SI_ChemRxiv.pdf
2021 02 Ivanova SI ChemRxiv
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ek20 sq-finalcif
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ek27 sq-finalcif
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si30 sq-finalcif
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2Me channel
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2Et channel
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2nBu channel