Thiol-methylsulfone-based Hydrogels for Cell Encapsulation: Reactivity Optimization of Aryl-methylsulfone Substrate for Fine-tunable Gelation Rate and Improved Stability

26 February 2021, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

We present novel thiol-methylsulfone hydrogels for cell encapsulation applications. The reactivity of the methylsulfonyl reactive partner has been optimized to improve the properties of the derived hydrogels for cell encapsulation.

Keywords

thiol-arylmethylsulfone
cell encapsulation
PEG hydrogels
water-based crosslinking reactions
gel stability
gelation kinetics

Supplementary materials

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