Cambridge Open Engage home
What is Cambridge Open Engage?
How to Submit
Browse
About
News [opens in a new tab]

Thiol-methylsulfone-based Hydrogels for Cell Encapsulation: Reactivity Optimization of Aryl-methylsulfone Substrate for Fine-tunable Gelation Rate and Improved Stability

26 February 2021, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

We present novel thiol-methylsulfone hydrogels for cell encapsulation applications. The reactivity of the methylsulfonyl reactive partner has been optimized to improve the properties of the derived hydrogels for cell encapsulation.

Keywords

thiol-arylmethylsulfone
cell encapsulation
PEG hydrogels
water-based crosslinking reactions
gel stability
gelation kinetics

Supplementary materials

Title
Description
Actions
Title
SuppInfo PaezJI
Description
Actions

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Now Published

Thiol-Methylsulfone-Based Hydrogels for Cell Encapsulation: Reactivity Optimization of Aryl-Methylsulfone Substrate for Fine-Tunable Gelation Rate and Improved Stability [opens in a new tab]
Julieta I. Paez, Adrián de Miguel-Jiménez, Rocío Valbuena-Mendoza, Aditi Rathore, Minye Jin, Alisa Gläser, Samuel Pearson, Aránzazu del Campo journal article
Biomacromolecules , Volume 22, Issue 7
Online publication date: Jun 06, 2021

Version History

Feb 26, 2021 Version 1

Version Notes

First version

Metrics

1,215
520
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
NC logo
NC
The content is available under CC BY NC 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.14115404.v1
D O I: 10.26434/chemrxiv.14115404.v1 [opens in a new tab]

Funding

Deutsche Forschungsgemeinschaft (DFG, Project no. 422041745)
Deutscher Akademischer Austauschdienst (DAAD, Exchange Internship Program)
European Union’s Horizon 2020 research and innovation programme under the FET PROACTIVE grant agreement no. 731957 (Mechano-Control)

Author’s competing interest statement

No conflict of interest

Share