Organic Chemistry

Preparation and Synthetic Applicability of Novel Imidazole-Containing Cyclic Iodonium Salts

Abstract

The novel approach to the preparation of imidazole-substituted cyclic iodonium salts has been developed via oxidative cyclization of 1-phenyl-5-iodoimidazole using cheap and available Oxone®/H2SO4 oxidative system. The structure of newly prepared compounds has been proved by X-ray monocrystal diffractometry revealing the characteristic surface features for cyclic iodonium salts. The prepared compounds demonstrated the high reactivity in the heterocyclization reactions with elemental sulfur affording benzo[5,1-b]imidazothiazoles with good yields.

Content

Thumbnail image of manuscript.pdf
download asset manuscript.pdf 0.79 MB [opens in a new tab]

Supplementary material

Thumbnail image of SI.pdf
download asset SI.pdf 13 MB [opens in a new tab]
SI