Organic Chemistry

α-Glucosidic Hydroquinone Derivatives from Viburnum Erosum


Six new compounds (1−6) were isolated from the leaves of Viburnum erosum along with four known compounds 7−10. The structures were determined by NMR and MS spectroscopic analyses, and their absolute configurations were established by chemical and spectroscopic methods. Compounds 1–6 were α-glucosidic hydroquinone derivatives with different linear monoterpenoid structures. Compounds 1−10 were also evaluated for their tyrosinase inhibitory activities, and 10 showed potent inhibition of tyrosinase enzyme with IC50 of 37.9 μM compared to 47.6 μM of the positive control (β-arbutin).


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Supplementary material

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Supplementary Information