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Coupling Miniaturized Free-Flow Electrophoresis to Mass Spectrometry via a Multi-Emitter ESI Interface

18 December 2020, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

We present a novel multi-emitter electrospray ionization interface for the coupling of microfluidic
free-flow electrophoresis (μFFE) with mass spectrometry. 15 sample streams coming from 15 μFFE outlets were continuously analyzed in quick succession to monitor the electrophoretic
separation in the microchip.

Keywords

Free-Flow Electrophoresis
Mass Spectrometric Analysis
electrospray ionization emitters
miniaturization devices

Supplementary materials

Title
Description
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Title
Jender Multi-Emitter-Interface Video
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Version History

Dec 18, 2020 Version 1

Version Notes

Version 1.0

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The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.13386758.v1
D O I: 10.26434/chemrxiv.13386758.v1 [opens in a new tab]

Funding

This study was supported by the “Ministerium für Kultur und Wissenschaft des Landes Nordrhein-Westfalen”, the “Regierenden Bürgermeister von Berlin – Senatskanzlei Wissenschaft und Forschung”, and the “Bundesministerium für Bildung und Forschung”, also in form of the Leibniz-Research Cluster (grant number: 031A360E).

Author’s competing interest statement

There are no conflicts to declare.

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