Influence of Bound Water on the Interaction of the Same-Nature and Different-Nature Chemical Groups of Drugs and Receptors

Felix S. Dukhovich; Mikhail Darkhovskii

doi:10.26434/chemrxiv.13252610.v1

Biological and Medicinal Chemistry

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Influence of Bound Water on the Interaction of the Same-Nature and Different-Nature Chemical Groups of Drugs and Receptors

02 December 2020, Version 1

Working Paper

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This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Role of water in thermodynamic of molecular recognition processes in the binding of a ligand to a receptor is extremely important. However, there is still a significant lack of specific knowledge to the extent of water influence on the process.

Keywords

receptor-ligand interactions

bound water

intermolecular energy

water-mediated recognition

drug-receptor recognition

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Dec 02, 2020 Version 1

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The content is available under CC BY NC ND 4.0

DOI

10.26434/chemrxiv.13252610.v1

Author’s competing interest statement

There is no conflict of interest

Influence of Bound Water on the Interaction of the Same-Nature and Different-Nature Chemical Groups of Drugs and Receptors

Authors

Abstract

Keywords

Comments

Version History

Version Notes

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License

DOI

Author’s competing interest statement

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