Working Paper
Authors
- Timothy Kench ,
- Peter A. Summers ,
- Marina K. Kuimova ,
- James Lewis ,
- Ramon Vilar
Imperial College London
Abstract
In this paper we report a unique approach to
control the DNA interactions, cellular uptake and cellular localisation of a
small molecule. We have designed rotaxanes that include a luminescent
DNA binder, a macrocycle that
modulates the DNA binding and a stopper that
can be cleaved by either light or the activity of an enzyme.
Content

Supplementary material

Rotaxane-G4-SupplementaryInformation