Mikania Mikrantha Leaf Extract Mediated Biogenic Synthesis of Magnetic Iron Oxide Nanoparticles: Characterization and Its Antimicrobial Activity Study

With an aim to introduce a new highly potent antimicrobial nanoparticles using an environment-friendly route, he present work reports the green synthesis of iron oxide nanoparticles (Fe₃O₄NPs) utilizing Mikania mikrantha leaf extract and its application as efficient antimicrobial agent. The green Fe₃O₄NPs have been described by X-beam diffraction (XRD), Ultraviolet-Visible (UV-Vis) spectroscopy, Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and Fourier Transform-Infra Red (FT-IR) investigation. The TEM image shows the rhomboidal Fe₃O₄NPs with average mean sizes 20.27 nm. The FT-IR investigation proved Fe₃O₄NPs have been balanced out through the associations of steroids, terpenoids, flavonoids, phenyl propanoids, phenolic acids and proteins present in the leaf extract. The synthesized Fe₃O₄NPs shows a very high antibacterial and antifungal property against 5 bacterial strains such as Bacillus cereus, Acinetobacter johnsonii, Pseudomonas aeruginosa, Achromobacter spanius and Chromobacterium pseudoviolaceum strain, and 4 fungal strains (Aspergillus niger, Penicillium citirinum, Fusarium oxysporium, and Candida albicans). The green synthesized iron oxide nanoparticles can interfere metabolic activities of microorganisms which determine its antimicrobial properties and could bring a promising application in the fields of medicine.