Biological and Medicinal Chemistry

Collaborative Virtual Screening to Elaborate an Imidazo[1,2-A]pyridine Hit Series for Visceral Leishmaniasis

Abstract

An innovative pre-competitive virtual screening collaboration was engaged to validate and subsequently explore an imidazo[1,2-a]pyridine screening hit for visceral leishmaniasis. Parasitology and early ADME data is presented.

Version notes

v1 - submitted for peer review

Content

Thumbnail image of Akao et al Oct 2020 preprint format.pdf

Supplementary material

Thumbnail image of SI 1 intro and assays final.pdf
SI 1 intro and assays final
Thumbnail image of SI 2 - Table of compounds final.pdf
SI 2 - Table of compounds final
Thumbnail image of SI 3 - experimental final.pdf
SI 3 - experimental final
Thumbnail image of SI 4 - Analytical data final.pdf
SI 4 - Analytical data final