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Collaborative Virtual Screening to Elaborate an Imidazo[1,2-A]pyridine Hit Series for Visceral Leishmaniasis

04 November 2020, Version 1

Abstract

An innovative pre-competitive virtual screening collaboration was engaged to validate and subsequently explore an imidazo[1,2-a]pyridine screening hit for visceral leishmaniasis. Parasitology and early ADME data is presented.

Keywords

Infectious Disease
Medicinal Chemistry
In silico
Leishmania donovani
leishmaniasis treatment
Collaboration Networks Community structures

Supplementary materials

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Description
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SI 1 intro and assays final
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SI 2 - Table of compounds final
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SI 3 - experimental final
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SI 4 - Analytical data final
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Version History

Nov 04, 2020 Version 1

Version Notes

v1 - submitted for peer review

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License

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The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.13134785.v1
D O I: 10.26434/chemrxiv.13134785.v1 [opens in a new tab]

Funding

GHIT

Author’s competing interest statement

There are no conflicts of interest to declare

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