Insight into the Scope and Mechanism for Transmetallation of Hydrocarbyl Ligands on Complexes Relevant to C-H Activation

22 September 2020, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

We report the transmetallation of hydrocarbyl fragments (Me, Bn, Ph) from a variety of organo-metallic complexes relevant to C-H activation (Ir, Rh, W, Mo) to Pt(II) electrophiles. The scope of suitable hydrocarbyl donors is remarkable in that three different classes of organometallics with widely varying reactivity all undergo the same general reaction with Pt(II) electrophiles. A competitive substituent effect experiment reveals faster transmetallation of more electron rich hydrocarbyl groups. A sterochemical probe reveals that transmetallation to Hg(II) proceeds with retention of stereochemistry. This study suggests that transmetallation could provide a viable path for catalytic function- alization of stable complexes resulting from C-H bond activation and other processes.

Keywords

transmetallation
C-H functionalization
mechanism
dual catalysis

Supplementary materials

Title
Description
Actions
Title
TM scope SI
Description
Actions

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.