Expanding the Scope of Palladium-Catalyzed B – N Cross- Coupling Chemistry in Carboranes

02 September 2020, Version 2
This content is a preprint and has not undergone peer review at the time of posting.


Here we show that azide, sulfonamide, cyanate, and phosphoramidate nucleophiles can be straightforwardly cross-coupled onto the B(9) vertices of the o- and m-carborane core from readily accessible precursors without significant deboronation by-products, laying the

groundwork for further study into the utility and properties of these new B-aminated carborane species.


Buchwald-Hartwig amination
biaryl ligand
boron cluster


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