Theoretical Study of the Optical Spectra of SARS-CoV-2 Proteins

11 June 2020, Version 1
This content is a preprint and has not undergone peer review at the time of posting.


Treatment for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes Covid-19, may well be predicated on knowledge of the structures of protein of this virus. However, often these cannot be determined easily or quickly. Herein, we provide calculated circular dichroism (CD) spectra in the far- and near-UV, and infra-red (IR) spectra in the amide I region for experimental structures and computational models of SARS-CoV-2 proteins. The near-UV CD spectra offer greatest sensitivity in assessing the accuracy of models.


circular dichroism
amide I

Supplementary materials

SI SARS COV 2 computedCD IR


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