Working Paper
Authors
- Jie Feng ,
- Ding Du
China Pharmaceutical University ,
- Kuili Zhang ,
- Jian Gao ,
- Tao Lu ,
- Rui Ma ,
- Zhihao Shi
Abstract
An NHC and photo-redox co-catalyzed α-amino acid
decarboxylative carbonylation reaction was presented here. This method displayed
good scope generality, providing an easy and direct pathway to access various
downstream α-amino ketones from readily accessible starting materials under bio- and medicinally compatible conditions. Moreover, this
strategy is appealing to chemical biology since it
has great potential for chemical modification of peptides or late-stage
synthesis of keto-peptides.
Content

Supplementary material

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manuscript-2020-6-7bydingdu
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