Cambridge Open Engage home
What is Cambridge Open Engage?
How to Submit
Browse
About
News [opens in a new tab]

Enantiomeric Excess Dependent Splitting of NMR Signal Through Co-Ligand Dynamic Exchange in a Coordination Complex

28 April 2020, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

A coordination complex (L·2Zn·3C), where L is a prochiral ligand and C is an exchangeable acetate co-ligand, exhibits symmetrical splitting of 1H-NMR resonances due to L, which is proportional to the enantiomeric excess (ee) of a chiral guest co-ligand, 2-phenoxypropionic acid (PPA). The NMR resonances remain split even in dilute solution due to the high stability of complex with chiral guest.

Keywords

chirality detection
prochirality
NMR
chirality transfer
Coordination chemistry
enantiomeric excess
Titration

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Now Published

Enantiomeric Excess Dependent Splitting of NMR Signal through Dynamic Chiral Inversion and Coligand Exchange in a Coordination Complex [opens in a new tab]
Kazuyoshi Takimoto, Shinsuke Ishihara, Jan Labuta, Václav Březina, Daniel T. Payne, Jonathan P. Hill, Katsuhiko Ariga, Masato Sumita, Shigeki Mori, Hisako Sato journal article
The Journal of Physical Chemistry Letters , Volume 11, Issue 19
Online publication date: Sep 09, 2020

Version History

Apr 28, 2020 Version 1

Version Notes

This is the first version

Metrics

2,338
446
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
NC logo
NC
ND logo
ND
The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.12198945.v1
D O I: 10.26434/chemrxiv.12198945.v1 [opens in a new tab]

Funding

JSPS KAKENHI Grant No. JP16H06518 (Coordination Asymmetry), and Grant No. 19K05229

Author’s competing interest statement

There is no conflict of interest.

Share