Exploring the Active Compounds of Traditional Mongolian Medicine in Intervention of Novel Coronavirus (2019-nCoV) Based on Molecular Docking Method

25 February 2020, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

In this study, a research strategy combining network pharmacological analysis, protein docking and molecular docking virtual computation was adopted. It was found that phillyrin and chlorogenic acid could block the combination of 2019-nCoV S-protein and ACE2 at the molecular level. Both can be used as potential inhibitors of 2019-nCoV for further research and development.

Keywords

Mongolian medicine
chlorogenic acid
2019-nCoV
S-protein
ACE2
phillyrin

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