Biological and Medicinal Chemistry

Genetically Tunable Enzymatic C‒H Amidation for Lactam Synthesis

Authors

Abstract

Directed evolution of cytochrome P450 enzymes fine-tunes site selectivity of new-to-nature C‒H amidation for modular, sustainable and scalable preparation of enantio-enriched β-, γ- and δ-lactams.

Content

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