Effective Plasmonic Coupling and Propagation Facilitates Ultrasensitive and Remote Sensing Using Surface Enhanced Raman Spectroscopy

20 December 2019, Version 1
This content is a preprint and has not undergone peer review at the time of posting.


Surface-enhanced Raman spectroscopy (SERS) is a sensitive technique for the detection of analytes through light scattering that is enhanced by chemical and electromagnetic effects through interactions on surfaces, particularly in nano-gaps. Herein we show that dissolved oxygen is the strongest attenuator of the SERS response in aqueous solution and its removal by chemical means can lower the detection limit by 109–1010 times, to achieve unprecedented sensitivity, i.e., detection of a single molecule in ~300 µL of sample solution. It also enables remote detection of the analyte outside of the field of view of the incident laser beam, e.g., over a distance of 1 m, which we propose is due to the coupling of the plasmonic field within and between nanoparticle aggregates, allowing for signal transmission throughout the sample volume.


Surface Enhanced Raman Spectroscopy
Oxygen Removal
Remote Sensing
Single Molecule Detection

Supplementary weblinks


Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.