Catalysis

Synthesis of Conjugated Triynes via Alkyne Metathesis

Abstract

The synthesis of conjugated triynes by molybdenum-catalyzed alkyne metathesis is reported. Strategic to the success of this approach is the utilization of sterically-hindered diynes that allowed for the site- selective alkyne metathesis to produce the desired con- jugated triyne products. The steric hindrance of alkyne moiety was found to be crucial in preventing the for- mation of diyne byproducts. This novel synthetic strategy was amenable to self- and cross-metathesis providing straightforward access to the corresponding symmetrical and dissymmetrical triynes with high selectivity.

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Content

Thumbnail image of Triynes 2019 (ChemRxiv).pdf

Supplementary material

Thumbnail image of SI_Triynes ChemRxiv.pdf
SI Triynes ChemRxiv