Direct Access to (±)-10-Desbromoarborescidine A from Tryptamine and Pentan-1,5-diol

17 December 2019, Version 1
This content is a preprint and has not undergone peer review at the time of posting.


A single step synthetic strategy for (±)10- Desbromoarborescidine A is described. Starting from tryptamine and pentan-1,5-diol, this acceptorless dehydrogenative condensation process is efficiently catalyzed by a ruthenium complex featuring proton-responsive phosphine pyridone ligand.
Manuscript is available supporting material is available and includes experimental procedures, characterization of compounds, 1H, 13C NMR spectra and chromatograms.


Green Chemistry Approach
Natural products
Homogeneous Catalysis
hydrogen transfer

Supplementary materials

Supporting Information Desbromoarborescidine Modified Apurba 2019 12 09


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