Biological and Medicinal Chemistry

A Sweet Galactose Transfer – Metabolic Oligosaccharide Engineering as a Tool to Study Glycans in Plasmodium Infection

Authors

Abstract

The use of artificial galactose derivatives and labelling through iEDDA reaction in the liver stage of Plasmodium infection showed increased uptake in infected hepatic cells, through participation of GLUT1 transporters. Furthermore, unprotected derivatives are transferred from the mosquito host to the Plasmodium berghei parasite. This strategy has the potential to provide new insights into Plasmodium glycobiology.

Content

Thumbnail image of Manuscript.pdf

Supplementary material

Thumbnail image of TOC.png
TOC
Thumbnail image of Supporting Information.pdf
Supporting Information