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Catalysis

Decarboxylative C–C and C–N Bond Formation via Ligand-Accelerated Iron Photocatalysis

Working Paper

Authors

Abstract

Through iron photocatalysis, a mild and effective protocol for the decarboxylative C–C and C–N bond formation has been achieved. The carboxylic acids readily underwent radical decarboxylation in the presence of Fe2(SO4)3 and di-(2-picolyl)amine with visible light irradiation. The resultant alkyl radicals then reacted with Michael acceptors or azodicarboxylates to furnish the adducts.

Version notes

The first version for Chemrxiv.

Content

Supplementary material

Supporting Information Fe

Supplementary weblinks

https://pubs.acs.org/doi/10.1021/acs.orglett.9b01439

Version History

Sep 13, 2019 Version 1

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License

CC logo BY logo NC logo ND logo
The content is available under CC BY NC ND 4.0 License CreativeCommons.org [opens in a new tab]

DOI

10.26434/chemrxiv.9816950.v1
D O I: 10.26434/chemrxiv.9816950.v1 [opens in a new tab]

Funding

Natural Science Foundation of Shanghai (19ZR1468700)

Author’s competing interest statement

The authors declare no competing financial interest.

Keywords

Ligand-Accelerated
Iron Photocatalysis
Decarboxylative
C–C Bond Formation
C–N Bond Formation

Publication

This content is an early or alternative research output and has not been peer-reviewed at the time of posting.