Beta-Amino Phosphine Mn Catalysts for 1,4-Transfer Hydrogenation of Chalcones and Allylic Alcohol Isomerization

09 August 2019, Version 1
This content is a preprint and has not undergone peer review at the time of posting.


Beta-amino phosphines derived from amino-acids are excellent supporting ligands for Mn(I) transfer hydrogenation catalysts. Namely, a variety of ketones and chalcones are efficiently reduced under mild conditions (2-propanol, 3 h, 60 °C). Moreover, chalcones are selectively reduced to the saturated ketone in 2-propanol and allylic alcohols are quantitatively converted into the same product in toluene.


Transfer hydrogenation
phosphine ligand
Allylic Alcohols


Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.