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Intermolecular Aminoallylation of Alkenes Using Allyl-Oxyphthalimide Derivatives: A Case Study in Radical Polarity Effects

05 July 2019, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

A case study on the polarity effects of radical mediated intermolecular alkene aminoallylation is presented herein. This radical group transfer method pairs vinyl ethers with electronically deficient allyl-oxyphthalimide derivatives to give difunctionalized products while illustrating the guiding effects of polarity on this radical reactivity.

Keywords

radical chemistry
polarity effects
aminoallylation
O-atom transfer
phosphite

Supplementary materials

Title
Description
Actions
Title
2019-07-03-AA-ChemRxiv-SI
Description
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Now Published

Intermolecular Aminoallylation of Alkenes Using Allyl‐Oxyphthalimide Derivatives: A Case Study in Radical Polarity Effects [opens in a new tab]
Samuel W. Lardy, Valerie A. Schmidt journal article
European Journal of Organic Chemistry , Volume 2019, Issue 40
Online publication date: Oct 17, 2019

Version History

Jul 05, 2019 Version 1

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The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.8479250.v1
D O I: 10.26434/chemrxiv.8479250.v1 [opens in a new tab]

Funding

University of California San Diego start-up funds

Author’s competing interest statement

The authors declare no competing financial interest

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