Modification of Chitosan Based on Computer Simulation and Its Application as Biomaterial

28 June 2019, Version 1
This content is a preprint and has not undergone peer review at the time of posting.


Modification of chitosan has become an important means to obtain chitosan polymers with better properties. In recent years, the application properties of chitosan have been greatly improved by modification, crosslinking, grafting and other modification methods. In order to improve its poor solubility and weak stability and expand its application scope, physical and chemical methods are often used to modify chitosan. As an important natural biomaterial, the modification and application of chitosan have attracted wide attention. This paper briefly summarizes the degradation and modification methods of chitosan at home and abroad and its research results in biomedicine. The interaction of the interface of the knife polymer composite system and the bonding effect of the coupling agent on the interface of the composite were analyzed by computer simulation. The simulation results show that the interaction between the surface and the three polymer segments is the strongest. These results indicate that chitosan is a kind of biomaterial with excellent performance and has broad application prospects.


Computer simulation


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