Organic Chemistry

A Metal-Free Facile Construction of C(sp3) –CF3 Bond: Trifluoromethylation of Hydrazones with Togni’s Reagent under Mild Conditions

Authors

Abstract

A metal-free trifluoromethylation of hydrazones with Togni’s reagent under mild conditions was developed. Various functional groups including ester, methoxy, dimethoxy, nitro, halogen and heterocyclic compounds were tolerated. This simple and green strategy provides a practical tool to construct C(sp3) –CF3 bonds

Content

Thumbnail image of Manuscript submitted to ChemRxiv.pdf

Supplementary material

Thumbnail image of Supporting Information 0615.pdf
Supporting Information 0615