Catalysis

Hydroalkylation of Olefins to form Quaternary Carbons

Abstract

Metal-hydride hydrogen atom transfer (MHAT) functionalizes unbiased alkenes with predictable branched (Markovnikov) selectivity. The breadth of these transformations has been confined to π-radical traps; no sp3 electrophiles have been reported. Here we describe a Mn/Ni dual catalytic system that allows for the hydroalkylation of unactivated olefins by unactivated alkyl halides, yielding aliphatic quaternary carbons.

Content

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Supplementary material

Thumbnail image of SI - Experimental Section and Notes.pdf
SI - Experimental Section and Notes
Thumbnail image of SI - NMR Spectra.pdf
SI - NMR Spectra