Visible-Light-Induced Oxidative Cleavage of C-C Triple Bond via Hydroamination: Direct Synthesis of Oxamates from Amines and Activated Alkynes

The direct oxidative cleavage of activated alkynes via hydroamination has been described using organic photocatalyst under visible-light irradiation at room temperature. In this reaction, the single electron oxidation of an insitu formed enamines undergo radical coupling with oxidant which finally delivers the oxamates. The key features of this photocatalytic reaction are the mild reaction conditions, metal-free organic dye as photocatalyst, TBHP plays dual role as “O” source and for the regeneration of photocatalyst.