A Metric Space Approach on the Molecular vs. Chemical Similarity of Some Analgesic and Euphoric Compounds

04 January 2019, Version 1
This content is a preprint and has not undergone peer review at the time of posting.


There is a relentless effort on gaining information on the reason why some compounds could cause similar effects though they are or not structural similar. That is the chemical similarity that plays an equally important role and we approach it via metric space theory on a set of analgesic drugs and euphoric compounds. The findings of the present study are in agreement to these obtained via traditional structural indices moreover are in accord with clinical findings.


Metric Space
Structural Similarity
Chemical Similarity


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