Analytical Chemistry

A Boronic Acid-Based Fluorescence Hydrogel for Monosaccharide Detection

Abstract

A boronic acid-based anthracene fluorescent probe was functionalised with an acrylamide unit to incorporate into a hydrogel system for monosaccharide detection. In solution, the fluorescent probe displayed a strong fluorescence turn-on response upon exposure to fructose, and an expected trend in apparent binding constants, as judged by a fluorescence response where D-fructose > D-galactose > D-mannose > D-glucose. The hydrogel incorporating the boronic acid monomer demonstrated the ability to detect monosaccharides by fluorescence with the same overall trend as the monomer in solution with the addition of fructose resulting in a 10-fold enhancement (≤ 0.25 M).

Content

Thumbnail image of Suying 07102018.pdf

Supplementary material

Thumbnail image of Suying ESI 07102018.pdf
Suying ESI 07102018