Cambridge Open Engage home
What is Cambridge Open Engage?
How to Submit
Browse
About
News [opens in a new tab]

Can Gold Nanoparticles Aid Electrophoretic Detection of Sulphur in Biomolecules? Development of Gold-PAGE

05 April 2018, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

The prevalence, distinctive reactivity, and biological significance of sulphur-based groups in proteins and nucleic acids means that analysis of sulphur is of prime importance in biochemistry, biotechnology, and medicine. We report steps in the development of a method to detect these moieties using gold nanoparticles as adjuncts in polyacrylamide gel electrophoresis (Gold-PAGE).

Keywords

Gold Nanoparticles
Gel electrophoresis
DNA affinity

Supplementary materials

Title
Description
Actions
Title
Gold-PAGE preprint ESI
Description
Actions

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Now Published

Development of Gold-PAGE: towards the electrophoretic analysis of sulphurous biopolymers [opens in a new tab]
Emerald R. Taylor, Silvia Cavuoto, David M. Beal, Sophie Caujolle, Adrian Podoleanu, Christopher J. Serpell journal article
Journal of Materials Chemistry B , Volume 7, Issue 34
Online publication date: 2019

Version History

Apr 05, 2018 Version 1

Metrics

3,307
585
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
NC logo
NC
ND logo
ND
The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.6086531.v1
D O I: 10.26434/chemrxiv.6086531.v1 [opens in a new tab]

Funding

E. R. Taylor thanks the Leverhulme Trust for support under a Research Project Grant (RPG-2017-188). We are grateful for the University of Kent and the Royal Society of Chemistry Research Fund for monetary support. D. M. Beal thanks the BBSRC (BB/M009815/1) for financial support. S. Caujolle and A. Podoleanu acknowledge the UBAPHODESA Marie Curie European Industrial Doctorate 607627.

Author’s competing interest statement

There are no conflicts of interest to declare.

Share