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Unrestrictive protein modification localization and quality control for open search of mass spectra

18 January 2018, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

We have developed PTMiner, a first software tool for automated, confident filtering, localization and annotation of protein post-translational modifications identified by open (mass-tolerant) search of large tandem mass spectrometry datasets. The performance of the software was validated on carefully designed simulation data.

Keywords

post-translational modifications
false discovery rates
unrestrictive modification localization
open search
Chemistry

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Version History

Jan 18, 2018 Version 1

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The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.5797995.v1
D O I: 10.26434/chemrxiv.5797995.v1 [opens in a new tab]

Author’s competing interest statement

No conflict of interest

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