Fluorous photosensitizers enhance photodynamic therapy with perfluorocarbon nanoemulsions

08 September 2017, Version 1
This content is a preprint and has not undergone peer review at the time of posting.


Photodynamic therapy (PDT) requires photosensitizer, light, and oxygen to induce cell death. The majority of efforts to advance PDT focus only on the first two components. Here, we employ perfluorocarbon nanoemulsions to simultaneously deliver oxygen and photosensitizer. We find that the implementation of fluorous soluble photosensitizers enhances the efficacy of PDT.


photodynamic therapy
perfluorocarbon nanoemulsions
singlet oxygen


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