Inorganic Chemistry

The Phospha-Bora-Wittig Reaction



Here, we report the phospha-bora-Wittig reaction for the direct preparation of phosphaalkenes from aldehydes, ketones, esters, or amides. The transient phosphaborene Mes*P=B-NR2 reacts with carbonyl compounds to form 1,2,3-phosphaboraoxetanes, analogues of oxaphosphetane intermediates in the classical Wittig reaction. 1,2,3-phosphaboraoxetanes undergo thermal or Lewis acid/base-promoted cycloreversion, yielding phosphaalkenes. Experimental and density functional theory studies reveal far-reaching similarities between classical and phospha-bora-Wittig reactions.

Version notes

version 1.0


Thumbnail image of chemarxiv.pdf

Supplementary material

Thumbnail image of
Thumbnail image of Supporting Information - final.pdf
Supporting Information - final