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[89Zr]Zr(oxinate)4 Allows Direct Radiolabelling and PET Imaging of Small Extracellular Vesicles

preprint
submitted on 28.07.2020 and posted on 29.07.2020 by Azalea Khan, Francis Man, Farid Faruqu, Jana Kim, Fahad Al-Salemee, Alessia Volpe, Gilbert O. Fruhwirth, Khuloud T. Al-Jamal, Rafael T. M. de Rosales
89Zr]Zr(oxinate)4 allows direct radiolabelling of exosomes/small extracellular vesicles (sEVs) and in vivo PET-CT imaging

Funding

UK Medical Research Council (MRC) [MR/N013700/1]

King’s College London MRC Doctoral Training Partnership in Biomedical Sciences

Next generation molecular imaging and therapy with radionuclides

Engineering and Physical Sciences Research Council

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Probing Multiscale Complex Multiphase Flows with Positrons for Engineering and Biomedical Applications

Engineering and Physical Sciences Research Council

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Wellcome/EPSRC Centre for Medical Engineering [WT/203148/Z/16/Z]

KCL and UCL Comprehensive Cancer Imaging Centre funded by CRUK and EPSRC in association with the MRC and DoH (England)

Wellcome Trust WT 084052/Z/07/Z

Wellcome Trust Multi User Equipment Grant: A multiuser radioanalytical facility for molecular imaging and radionuclide therapy research

National Institute for Health Research (NIHR) Biomedical Research Centre based at Guy's and St Thomas' NHS Foundation Trust and KCL [grant number IS-BRC-1215-20006]

History

Email Address of Submitting Author

rafael.torres@kcl.ac.uk

Institution

King's College London

Country

United Kingdom

ORCID For Submitting Author

0000-0003-0431-0535

Declaration of Conflict of Interest

No conflicts of interest declared

Version Notes

version 1.0

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