These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.
2 files

γ-Ray-Induced Proton Generation in Polymers: Quantifiable Single-Component Fluorescent Ratiometric Chemosensor

submitted on 24.12.2019 and posted on 24.12.2019 by Bin Pei, Biao Chen, Hao Su, Wenhuan Huang, Hui Miao, Yucai Wang, Xuepeng Zhang, Guoqing Zhang

Detection of g-rays is of vital significance in various areas such as high-energy physics, nuclear medicine, national security and space exploration. However, most current spectrometry methods are typically based on ionization effects which are limited to electron counting techniques. Herein, we report an alternative, quantifiable g-ray chemosensor from a g-ray-induced proton generation process more sensitive to poly (methyl methacrylate) (PMMA) and polyvinyl chloride (PVC) by surveying a series of commercially available polymers. Accordingly, a pH-sensitive yet g-ray-stable fluorophore is designed, resulting in dramatic fluorescence shift from the blue (lem = 460~480 nm) to the red region (lem = 570~620 nm) after subjecting it to g-irradiation in PMMA or PVC films. A linear response of ratiometric fluorescence intensity (Ired/Iblue) to g-ray dosage in a wide range (80-4060 Gy) was established, which can be used as a visual dosimeter. Meanwhile, the discovery also opens new doors for proton-based radiation detection and chemistry.


Email Address of Submitting Author


University of Science and Technology of China



ORCID For Submitting Author


Declaration of Conflict of Interest

No conflict