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EnT_Chemrxiv.pdf (811.36 kB)
Visible-Light Photosensitized Aryl and Alkyl Decarboxylative Carbon-Heteroatom and Carbon-Carbon Bond Formations
Preprints are manuscripts made publicly available before they have been submitted for formal peer review and publication. They might contain new research findings or data. Preprints can be a draft or final version of an author's research but must not have been accepted for publication at the time of submission.
revised on 22.04.2019 and posted on 23.04.2019by Frank Glorius, Tuhin Patra, Satobhisha Mukherjee, Jiajia Ma, Felix Strieth-Kalthoff
A general strategy to access both aryl and alkyl
radicals by photosensitized decarboxylation of the corresponding carboxylic
acids esters has been developed. An energy transfer mediated homolysis of
unsymmetrical sigma-bonds for a concerted
fragmentation/decarboxylation process is involved. As a result, an independent
aryl/alkyl radical generation step enables a series of key C-X and C-C bond forming reactions by
simply changing the radical trapping agent.