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Viscoelastic Phase Patterning in Artificial Protein Hydrogels

preprint
submitted on 18.11.2020, 19:30 and posted on 19.11.2020, 12:41 by Peter Rapp, Bradley Silverman
Viscoelastic forces can affect the dynamics of pattern formation during phase separation in polymeric materials. We programmed an artificial protein hydrogel to undergo viscoelastic phase separation above a critical temperature. Highly dynamic phase patterns that coarsened under the influence of viscoelastic stresses spontaneously emerged in these gels. Local oxidative crosslinking promoted by mild photobleaching could be used to initiate phase separation locally, enabling the creation of non-equilibrium patterns that evolved under the influence of surface tension and viscoelastic stresses to yield dynamic structures of controlled size and shape.

Funding

DMR-1506483

History

Email Address of Submitting Author

peter.rapp@yale.edu

Institution

California Institute of Technology

Country

United States of America

ORCID For Submitting Author

0000-0002-9586-2126

Declaration of Conflict of Interest

None

Version Notes

v1.0, submitted 11/18/20

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