These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.
Using HOESY NMR Spectroscopy to Characterise Pre-Nucleation Aggregates
preprintsubmitted on 30.12.2020, 08:37 and posted on 30.12.2020, 13:01 by Raitis Bobrovs, Andrievs Auseklis Auzins, Laura Drunka, Rimants Metlans, Ruslans Muhamadejevs, Kristaps Jaudzems
Pre-nucleation aggregates are important species on the crystallisation pathway. Here we combine heteronuclear Overhauser effect spectroscopy (HOESY) and molecular dynamics calculations to study the self-association of a model system – benzoic acid. Our findings indicate that heteronuclear Overhauser effects arise from diffusion-limited pre-nucleation aggregates and that self-association is solvent dependant.
From molecules to crystals: Molecular self-association by crystallization from solutions
Ministry of Education and ScienceFind out more...