These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.
Unexpected dimeric form of 17 - hydroxylupanine - MS and crystallographic studies
preprintsubmitted on 08.10.2017, 08:49 and posted on 10.10.2017, 07:20 by Joanna Kurek, Beata Jasiewicz, Anrdzej Katrusiak
The bis-quinolizidine alkaloids such as sparteine, lupanine and their derivatives are produced by the plants of Leguminoseae family. 17-Hydroksylupanine can be obtained both: naturally (in reaction catalysed by enzyme) and synthetically. Our data demonstrate that 17-hydroxylupanine can exists in dimeric form. It is the first time that one of bisquinolisidine alkaloids exists in the dimeric form in a solid state. A structure of dimeric form was confirmed by EI MS mass spectra and X-ray analysis.
- Natural Products