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Treatment of COVID-19 patients: Justicia adhatoda leaves extract is a strong remedy for COVID-19 – Case report analysis and docking based study

preprint
submitted on 27.03.2020 and posted on 27.03.2020 by Abhrajit Bag, Arijit Bag
To find immediately applicable drug for the treatment of COVID-19 positive patients, a plausible life cycle of this virus is proposed from the analysis of few case reports. On the basis of this proposal and symptomatic similarities few common drug-molecules are tested as protease inhibitor and replicase inhibitor of COVID-19 virus using COVID-19 Docking Server. It is observed that anisotine and vasicoline of Justicia adhatoda and Pemirolast are very good inhibitors. As all these three compounds are market available drugs, immediate clinical trial is plausible which may lead to the golden success against the present pandemic. We prescribed different drugs for different purpose and stages of viral infection.

Key words: COVID-19, Structure of COVID-19, Infection mechanism of COVID-19, Model drugs for COVID-19, Docking study.

Funding

no funding

History

Email Address of Submitting Author

bagarijit@gmail.com

Institution

Maulana Abul Kalam Azad University of Technology

Country

India

ORCID For Submitting Author

0000-0002-0177-9605

Declaration of Conflict of Interest

There is no conflict of interests

Version Notes

draft version

Exports